Research
Area 5
Pathophysiology and Molecular Bases in Hematology
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Team manager
Dolors Colomer
(Hospital Clínic)
DCOLOMER(ELIMINAR)@clinic.ub.es
Strategic objectives
Epidemiologic, genetic, molecular and pathophysiologic study of malignant hemopathies and of erythrocyte pathology.
Main lines of research
1. Molecular bases of regulation of apoptosis induced by drugs in lymphoid cancers. Search for new strategies to treat these diseases.
2. Cytologic, immunophenotypic and molecular studies of malignant hemopathies. Development of new technologies for both diagnosing and monitoring minimal residual disease.
3. Promotion of cooperative strategies in the area of molecular diagnosis of leukemia and lymphomas.
4. Design and implementation of internal and external quality-control programs.
5. Cutaneous T and B-cell lymphomas. Clinical, histopathologic and immunophenotypic study. Prognostic factors and epidemiology.
6. Molecular study of congenital abnormalities of erythrocytes and the pathophysiologic mechanisms that play a role in the production and destruction of erythrocytes as a cause of anemia or erythrocytosis.
7. Genetic and epidemiologic study of hemoglobinopathies and thalassemias.