Research

Area 1

Inflammatory joint diseases (IJDs)

Team leader

Strategic objectives

Promotion of research into the most prevalent chronic forms of arthritis: rheumatoid arthritis (RA) and spondyloarthritis, including psoriatic arthritis.

Main lines of research

1. Prognostic factors in initial arthritis

  • Prognostic factors (clinical and immunogenetic) in patients with initial rheumatoid arthritis.
  • Production of new synthetic citrullinated peptides for the design of immunoassays with diagnostic and prognostic value in recent-onset rheumatoid arthritis.

2. Immunopathology of synovitis in chronic arthritis

  • Utility in differential diagnosis and prognosis. Immunopathological changes related to biological treatments. Synovial response biomarkers.

3. Role of synovial fibroblasts in arthritis refractory to antirheumatic treatment

4. Role of autoinflammatory genes in the pathogenesis of chronic arthritis

  • MEFV gene mutations in intermittent arthritis.