Research

Area 1

Molecular and cellular bases of inflammation. Structural and biological mass spectrometry.

Team leader

  • Daniel Closa
    (IIBB-CSIC)

Strategic objectives

Molecular and cellular bases of inflammation:
Study of inflammatory response in general.

Structural and biological mass spectrometry:
Development of techniques for solving problems in proteomics and in the analysis of biomolecules in general.
Application to the study of antigen presentation in autoimmune diseases and to the investigation of therapeutic targets and markers of the disease.

Main lines of research

Molecular and cellular bases of inflammation:

  • Mechanisms involved in the development of systemic inflammatory processes.
  • New therapies for idiopathic pulmonary fibrosis.
  • Study of the lipid alterations associated with pancreatitis.
  • Structural and biological mass spectrometry:

    • Phosphoproteomics of the human T lymphocyte.
    • Diagnostic and prognostic markers in cancer and other diseases.
    • External scientific-technical services.